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WORKS OF ALFRED I. COHN

PUBLISHED BY

JOHN WILEY & SONS.


Indicators and Test-papers.
Their Source, Preparation, Application, and Testsfor Sensitiveness. With Tabular Summary of the Applicationof Indicators. Second Edition, Revised andEnlarged. 12mo, ix + 267 pages. Cloth, $2.00.

Tests and Reagents.
Chemical and Microscopical, known by theirAuthors' Names; together with an Index of Subjects.8vo, iii + 383 pages. Cloth, $3.00.

TRANSLATIONS.

Fresenius's Quantitative Chemical Analysis.
New Authorized Translation of the latest GermanEdition. In two volumes. By Alfred I. Cohn,Phar.D. Recalculated on the basis of the latest atomicweights, and also greatly amplified by the translator.8vo, 2 vols., upwards of 2000 pages, 280 figures. Cloth,$12.50.

Techno-Chemical Analysis.
By Dr. G. Lunge, Professor at the EidgenössischePolytechnische Schule, Zurich. Authorized Translationby Alfred I. Cohn, Phar.D. 12mo, vii + 136 pages,16 figures. Cloth, $1.00.

Toxins and Venoms and Their Antibodies.
By Em. Pozzi-Escot. Authorized Translation byAlfred I. Cohn, Phar.D. 12mo, vii + 101 pages. Cloth,$1.00, net.


3

THE
TOXINS AND VENOMS
AND THEIR ANTIBODIES

BY
EM. POZZI-ESCOT

AUTHORIZED TRANSLATION
BY
ALFRED I. COHN, Phar. D.

FIRST EDITION
FIRST THOUSAND

NEW YORK
JOHN WILEY & SONS
London: CHAPMAN & HALL, Limited
1906

4

Copyright, 1906
BY
ALFRED I. COHN

ROBERT DRUMMOND, PRINTER, NEW YORK5


INTRODUCTION.

Our knowledge of the toxins is of quite recentdate. It is hardly twenty years since we began toacquire a knowledge of the facts that are detailedin this volume, and to which modern medicine owesits most recent and marvelous progress, particularlyin serotherapy.

In this volume we have studied, besides the truetoxins—substances of cellular origin and of albuminoidnature and unknown composition—othertoxic substances, the nitrogenized alkaloidal basesintroduced into science through the researches ofSelmi, Armand Gautier, and von Behring, andwhich are highly hydrogenized nitrogenous crystallizableprinciples of definite chemical composition—theproducts of the more or less advancedbreaking down of albuminoids.

Although these principles differ widely, by reasonof their physiological properties as a whole,from the toxic albuminoids, or true toxins, itappears proper to consider them as products of6the advanced decomposition of these toxins—andin this respect their study becomes imperative, themore so as they are very frequently encounteredtogether with the toxins, particularly in serpent-venoms,where their action is exerted in additionto that of the tr

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